Drawing biological molecules
Students learn how to draw the following molecules; glucose, ribose, saturated fatty acid and an amino acid. They answers questions which gives practice in recognition of each molecule activity. This is followed by an extension reading on vitalism and urea.
Are living organisms more than the sum of all the chemicals which make them?
Are biological chemicals more than the sum of the atoms in them?
Activity 1 - Drawing molecular diagrams
When drawing molecular diagrams which show all the atoms which make up a molecule and the way in which they are bonded together it is first important to know how many bonds each molecule has.
When drawing the biological molecules checking that each atom has the right number of bonds, will avoid mistakes.
A good way to remember the structures is to draw each diagram in three steps
- Draw the ring of carbon atoms (C)
- Add the oxygen (O) or the hydroxide (OH) - and nitrogen in an amino acid (N)
- Fill in all the remaining bonds with hydrogen (H) using the number of bonds above.
Drawing α-glucose (alpha-glucose)
Drawing β-glucose (beta-glucose)
Drawing a saturated fatty acid
Drawing an amino acid
Students can complete a copy of the diagrams on Student worksheet - drawing molecules
Activity 2 - The slaying of a beautiful hypothesis by an ugly fact
Read one or more of the following articles and make notes to explain how the synthesis of urea helped to disprove the theory of vitalism - the idea that there is a 'vital force' in living organisms as well as the biochemicals.
This article, kindly suggested by Troy Glover, is an excellent detailed account of the theory of vitalism:
This lesson could be a homework activity or a self study lesson.
Each of the molecules is shown in two diagrams both deliberately slightly different so that students realise that there is more than one way to represent the molecules. The carbon atoms have all been represented as C and the simplified stick diagrams have not been used.
This is lesson is not inquiry based but the hints with each drawing help students to make links between molecules and to find similar structures. Learning how to draw these molecules will involve some practice.
Pictionary or Articulate revision games
A fun way to practice drawing these diagrams might be to ask students to work in pairs and play a game of pictionary or articulate using the diagrams.
Pictionary. One student draws structures while the other guesses their names for a limited time, e.g. 1 minute. The winners are the team which guess most correct in the time.
Articulate. The students work again in pairs and take turns to describe the structures in words, without using the chemical names just the positions of the atoms in relation to one another. The winning pair are the ones who correctly identify the most molecules in 1 minute.